SrasV1, Main, Exploration, bibRecord, 001267

Preparedness for ebolavirus disease outbreak in Japan: Necessity of Biosafety level-4 facility.

Identifieur interne : 001267 ( Main/Exploration ); précédent : 001266; suivant : 001268

Preparedness for ebolavirus disease outbreak in Japan: Necessity of Biosafety level-4 facility.

Auteurs : Masayuki Saijo ; Kouichi Morita

Source :

Uirusu [ 0042-6857 ] ; 2015.

RBID : pubmed:26923962

Descripteurs français

KwdFr :
- Animaux, Ebolavirus (pathogénicité), Fièvre hémorragique à virus Ebola (), Fièvre hémorragique à virus Ebola (virologie), Flambées de maladies (), Humains, Japon, Protection civile, Sécurité, Virulence, Établissements de santé (tendances).
MESH :
- pathogénicité : Ebolavirus.
- tendances : Établissements de santé.
- virologie : Fièvre hémorragique à virus Ebola.
- Animaux, Fièvre hémorragique à virus Ebola, Flambées de maladies, Humains, Japon, Protection civile, Sécurité, Virulence.

English descriptors

KwdEn :
- Animals, Civil Defense, Disease Outbreaks (prevention & control), Ebolavirus (pathogenicity), Health Facilities (trends), Hemorrhagic Fever, Ebola (prevention & control), Hemorrhagic Fever, Ebola (virology), Humans, Japan, Safety, Virulence.
MESH :
- pathogenicity : Ebolavirus.
- prevention & control : Disease Outbreaks, Hemorrhagic Fever, Ebola.
- trends : Health Facilities.
- virology : Hemorrhagic Fever, Ebola.
- Animals, Civil Defense, Humans, Japan, Safety, Virulence.

Abstract

Although a globe box-type highly contained laboratory with the internationally-recognized biosafety level-4 standards has been constructed in the Murayama Annex, the National Institute of Infectious Diseases, Tokyo, Japan (NIID) in 1981, the laboratory has never been operated as BSL-4 laboratory since its construction. Furthermore, there are no other BSL-4 laboratories in operation in Japan. The evidence indicates that infectious BSL-4 pathogens such as Ebola and Marburg viruses cannot be manipulated in Japan, making it impossible to study the BSL-4 pathogens using the infectious viruses. A large-scale outbreak of ebolavirus disease (EVD) has occurred in the western Africa such as Guinea, Sierra Leone, and Liberia. Furthermore, the highly pathogenic pathogens' infectious diseases outbreaks such as SARS, Nipah encephalitis, Middle East respiratory syndrome (MERS) have emerged in the world. However, BSL-4 laboratories are not present in Japan, making it difficult to study these pathogens and infectious diseases. Because these emerging virus infections are caused by the zoonotic pathogens, the eradiation and the elimination of these infectious diseases are impossible. We need to develop the diagnostics, therapeutics, and preventive measures based on the studies of the highly pathogenic pathogens more in detail using the infectious microbes. Therefore, BSL-4 in operation in Japan is required to minimize the risk of and combat these emerging highly pathogenic pathogens' infectious diseases.

DOI: 10.2222/jsv.65.89
PubMed: 26923962

Affiliations:

Le document en format XML

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<term>Ebolavirus (pathogenicity)</term>
<term>Health Facilities (trends)</term>
<term>Hemorrhagic Fever, Ebola (prevention & control)</term>
<term>Hemorrhagic Fever, Ebola (virology)</term>
<term>Humans</term>
<term>Japan</term>
<term>Safety</term>
<term>Virulence</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Ebolavirus (pathogénicité)</term>
<term>Fièvre hémorragique à virus Ebola ()</term>
<term>Fièvre hémorragique à virus Ebola (virologie)</term>
<term>Flambées de maladies ()</term>
<term>Humains</term>
<term>Japon</term>
<term>Protection civile</term>
<term>Sécurité</term>
<term>Virulence</term>
<term>Établissements de santé (tendances)</term>
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<term>Hemorrhagic Fever, Ebola</term>
</keywords>
<keywords scheme="MESH" qualifier="tendances" xml:lang="fr"><term>Établissements de santé</term>
</keywords>
<keywords scheme="MESH" qualifier="trends" xml:lang="en"><term>Health Facilities</term>
</keywords>
<keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Fièvre hémorragique à virus Ebola</term>
</keywords>
<keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Hemorrhagic Fever, Ebola</term>
</keywords>
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<term>Civil Defense</term>
<term>Humans</term>
<term>Japan</term>
<term>Safety</term>
<term>Virulence</term>
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<term>Fièvre hémorragique à virus Ebola</term>
<term>Flambées de maladies</term>
<term>Humains</term>
<term>Japon</term>
<term>Protection civile</term>
<term>Sécurité</term>
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<front><div type="abstract" xml:lang="en">Although a globe box-type highly contained laboratory with the internationally-recognized biosafety level-4 standards has been constructed in the Murayama Annex, the National Institute of Infectious Diseases, Tokyo, Japan (NIID) in 1981, the laboratory has never been operated as BSL-4 laboratory since its construction. Furthermore, there are no other BSL-4 laboratories in operation in Japan. The evidence indicates that infectious BSL-4 pathogens such as Ebola and Marburg viruses cannot be manipulated in Japan, making it impossible to study the BSL-4 pathogens using the infectious viruses. A large-scale outbreak of ebolavirus disease (EVD) has occurred in the western Africa such as Guinea, Sierra Leone, and Liberia. Furthermore, the highly pathogenic pathogens' infectious diseases outbreaks such as SARS, Nipah encephalitis, Middle East respiratory syndrome (MERS) have emerged in the world. However, BSL-4 laboratories are not present in Japan, making it difficult to study these pathogens and infectious diseases. Because these emerging virus infections are caused by the zoonotic pathogens, the eradiation and the elimination of these infectious diseases are impossible. We need to develop the diagnostics, therapeutics, and preventive measures based on the studies of the highly pathogenic pathogens more in detail using the infectious microbes. Therefore, BSL-4 in operation in Japan is required to minimize the risk of and combat these emerging highly pathogenic pathogens' infectious diseases.</div>
</front>
</TEI>
<affiliations><list></list>
<tree><noCountry><name sortKey="Morita, Kouichi" sort="Morita, Kouichi" uniqKey="Morita K" first="Kouichi" last="Morita">Kouichi Morita</name>
<name sortKey="Saijo, Masayuki" sort="Saijo, Masayuki" uniqKey="Saijo M" first="Masayuki" last="Saijo">Masayuki Saijo</name>
</noCountry>
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Preparedness for ebolavirus disease outbreak in Japan: Necessity of Biosafety level-4 facility.

Preparedness for ebolavirus disease outbreak in Japan: Necessity of Biosafety level-4 facility.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration SRAS
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